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In a very recent review, we reported the identification as well as characterization of a completely new atypical opioid receptor with one of a kind adverse regulatory Houses to opioid peptides.one Our final results showed that ACKR3/CXCR7, hitherto generally known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is also a wide-sp